MSplus Foundation Reports on Recent MS Studies
One goal of the
MSplus Foundation is to educate its members and the public about research on
multiple sclerosis. The following articles feature some of the work being
Wisconsin Researchers Show that Thinly
Repaired Myelin Sheaths Restore Nerve Function and Persist for Years
Myelin sheaths that encase nerve fibers are
vital to nerve function and health. Finding ways to enhance the body’s ability
to repair myelin that has been damaged by the MS disease process is a priority
for restoring function. [More]
day before Thanksgiving in November of 1999, I woke up with my right side
temporarily paralyzed. Thinking I had a
stroke, my family doctor got me in that day.
After an examination, he made an appointment for me to be seen by a
neurologist the following Monday. [More]
Taking Vitamin D May Benefit People with Multiple Sclerosis
Taking a high dose of vitamin D3 is safe for people with multiple sclerosis and may help regulate the body’s hyperactive immune response, according to a pilot study published by Johns Hopkins physicians in the Dec. 30 online issue of Neurology, the medical journal of the American Academy of Neurology.
“These results are exciting, as vitamin D has the potential to be an inexpensive, safe and convenient treatment for people with MS,” says study author Peter Calabresi, M.D., director of the Johns Hopkins Multiple Sclerosis Center and professor neurology at the Johns Hopkins University School of Medicine. [More]
Flying Wheels Travel
Flying Wheels Travel provides people with physical disabilities, chronic illness or difficulty walking the opportunity to extend their lifestyle with unique travel and recreation destinations while empowering individuals and their family members to explore the world.
MSHelp.org Donor Closet
A Wonderful Resource!
The purpose of the "DONOR CLOSET" is to recycle used DURABLE MEDICAL EQUIPMENT (DME) & MOBILITY EQUIPMENT from people who no longer need or use the item. Many have up-graded, moved on to a more useable item, or otherwise no longer require the item. They donate the item to a person who needs it and has no financial means of purchasing it, or has been denied by an insurance company or government agency. [More]
MS Learn Online
Providing quality information and convenient access
Since its first broadcast in 1999, MS Learn Online, the National MS Society's Internet program, has been a successful way to educate about multiple sclerosis. View pre-recorded webcasts to learn more about MS from the convenience of your own home. Programs cover a wide variety of topics such as information for people newly diagnosed, MS basic facts, symptom management, employment, intimacy, care-partners, and progressive MS.
Each program may include:
New MS Learn Online webcasts are also available as podcasts. [More]
- Audio broadcast
- Slide presentation
- Program transcript (PDF format)
- Technical support instructions
- Additional resources
MS/Cancer Support Group discusses current MS research
In May 2017, MS/Cancer members learned about
three studies conducted on patients with Multiple Sclerosis (MS) to help its members
stay current on MS research.
These stories are from the National MS Society
website and links are provided after each study.
Finds That Cognitive Function in People with MS Improves with an Online Active
Cognitive Training Program
May 22, 2017
· In a trial funded by the National MS Society, researchers
found that a special online active cognitive training program improved
cognitive function in people with MS.
· Participants included 135 people with any type of MS who
were experiencing some cognitive problems. They used the training program for
60 hours over 12 weeks, in their own homes.
· This was the largest, controlled trial that has tested a
brain training program in people with MS. Future studies will help make clear
what types of training will have the best results, who will respond most
successfully, and how long benefits last.
· The team (Leigh Charvet, PhD, Lauren Krupp, MD, and
colleagues, now at NYU School of Medicine) published their findings in the open-access journal PLOS One on May 11,
Background: Cognitive problems
are common in people with MS. Among the cognitive functions that may be
affected are the ability to learn and remember information, to process
information quickly, and to organize, plan, and problem-solve.
Up to now there has not been an adequate treatment that successfully
meets the goal of improving the speed and accuracy of information processing to
improve performance in real-world situations. [More]
Important Nutrients in MS Management
including calcium and magnesium.
Michelle Leary-Chang was the guest speaker for a MS/Cancer conference call that
focused on patients with Multiple Sclerosis (MS) and nutrition, including
vitamin D. She is studying family medicine at Eastside Integrated Primary Care
in Bellevue, WA, and works part-time as a research associate at the Institute
of Functional Medicine. The following are highlights from her talk.
have MS. What should I do?
Choose an eating plan that is nutrient dense
and anti-inflammatory. [More]
Detailed Clinical Trial Results Published On Ocrelizumab for Primary Progressive and Relapsing MS
In our continuing effort to share
pertinent news about MS, the MS/Cancer Support Group featured this story during
our February 2016 members’ monthly conference call.
was published on the National MS Society website on December 22, 2016, and can
be found at www.nationalmssociety.org/About-the-Society/News/Detailed-Clinical-Trial-Results-Published-On-Ocrel.
from three clinical trials of the experimental therapy ocrelizumab have been
published, showing benefits in people with PPMS and RRMS and providing
additional details regarding effectiveness and safety, after preliminary
findings were reported at medical conferences.
in primary progressive MS is the first large-scale clinical trial to show
positive results in people with PPMS. The studies were published in two papers
in the December 21, 2016 issue of the New England Journal of Medicine:
“Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis” (Dr.
Xavier Montalban and others); “Ocrelizumab versus Interferon Beta-1a in
Relapsing Multiple Sclerosis” (Dr. Stephen Hauser and others).
agencies are now evaluating these results. The U.S. [More]
Over-the-counter drug may reverse chronic vision damage caused by multiple sclerosis
MSplus shares preliminary trial findings
Academy of Neurology published findings about people with multiple sclerosis (MS) and chronic vision damage. A common antihistamine, called clemastine
fumarate, is used to treat symptoms of allergies and the common cold.
Clemastine fumarate partially reversed damage to the visual system in people
with multiple sclerosis in a preliminary study.
The following is the article, which was published by Science Daily, and
can be found at https://www.sciencedaily.com/releases/2016/04/160412211123.htm#.V2g6eIEmy94.email
Over-the-counter drug may reverse chronic vision
damage caused by multiple sclerosis
A common antihistamine used to treat
symptoms of allergies and the common cold, called clemastine fumarate,
partially reversed damage to the visual system in people with multiple
sclerosis (MS) in a preliminary study released today that was presented at the
American Academy of Neurology's 68th Annual Meeting in Vancouver, Canada, April
The study involved people with MS and
optic neuropathy, which is damage to the nerve that sends information from the
eye to the brain. In people with MS, the immune system destroys myelin, the
protective coating around the nerves, which then leads to damage along the
nerves, slowing signals to and from the brain. Optic nerve damage is a common
consequence of the disease.
"This study is exciting because
it is the first to demonstrate possible repair of that protective coating in
people with chronic demyelination from MS," said study author Ari Green,
MD, of the Multiple Sclerosis Center at UC San Francisco, and a member of the
American Academy of Neurology. [More]
Small Trial Shows Estriol, A Pregnancy Hormone,
Reduces MS Lesion Activity In Women With MS
Summary: In a small-scale, early-phase trial of the hormone estriol, a form of estrogen, women with relapsing-remitting MS showed decreases in MRI-detected brain lesion activity and immune responses during treatment, suggesting that additional study of estriol is called for to determine longer-term efficacy and safety.
- Women who have MS and are pregnant often experience fewer MS symptoms and relapses, especially during the second and third trimester. Because the hormone estriol is elevated during later stages of pregnancy, and mice given pregnancy levels of estriol were shown to have fewer symptoms of an MS-like disease, the hormone was considered as a candidate for testing against MS.
- Estriol was well tolerated. Six women with relapsing-remitting MS experienced significant decreases in brain lesion numbers and volume, as well as reductions in levels of immune proteins indicative of inflammation. [More]
CDC provides info about MS and Cancer risk
Dr. Matthew M. Zack of the Division of Chronic Disease and Health Promotion for the Centers for Disease Control and Prevention has provided extensive references from MEDLINE that show studies of the risk of cancer associated with multiple sclerosis since 1966. [More]